You are bound to fail...you are wrong very often...But when you are right, it’s really good.
— Stanley Falkow

 

For current list of publications go here.

 

Publications 

Napier BA, Andres-Terre M*, Massis L*, Hryckowian AJ, Higginbottom SK, Cumnock K, Casey KM, Lugo KA, Schneider DS, Sonnenburg JL, & Monack DM (2019). Western diet regulates immune status and the response to LPS-driven sepsis independent of the diet-associated microbiome.  PNAS. In publication. *, authors contributed equally.

Napier BA and Monack DM (2017) Generating a RAW264.7 CRISPR-Cas9 genome-wide library. Bio protoc. 2017. May 20;7(10). pii: e2320. doi: 10.21769/BioProtoc.2320.

Napier BA and Monack DM. (2017) The sum of all defenses: Tolerance + Resistance.  Pathog Dis. 2017 Mar 1;75(2). doi: 10.1093/femspd/ftx015.

Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennet ML, Münch AE, Chung WS,  Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch D, Dawson TM, Stevens B, Barres BA. (2017) Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18.

Napier BA, Brubaker SW, Sweeney T, Gertsvolf NA, Monnett P, Rothmeier GH, Puschnik A, Carette JE, Khatri P, Monack DM. (2016) Complement pathway enhances caspase-11-dependent cell death and sepsis severity. J Ex Med. 2016. Oct 3. pil. jem.20160027.

Napier BA and Monack DM. (2016). A lipid arsenal to control inflammation. Science. 352(6290):1173-4.

Band VI*, Crispell EK*, Napier BA, Herrera CM, Tharp GK, Vavikolanu K, Pohl J, Read TD, Bosinger SE, Trent MS, Burd EM, Weiss DS. (2016). Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae. Nature Microbio. DOI: 10.1038/NMICROBIOL.2016.53. *, authors contributed equally.

Chin CY, Gregg KA, Napier BA, Ernst RK, Weiss DS. (2015) A PmrB-regulated deacetylase required for lipid A modification and polymyxin resistance in Acinetobacter baumannii. Antimicrob Agents Chemother. 00515-15.

Napier RJ, Norris BA, Swimm A, Giver CR, Harris WAC, Laval J, Napier BA, Patel G, Crump R, Peng Z, Bornmann W, Pulendra B, Buller RM, Weiss DS, Tirouvanziam R, Waller EK, Kalman D. (2015) Low doses of Imatinib induce myelopoiesis and enhance host antimicrobial immunity. PLoS Pathogens. 11(3):e1004770.

Napier BA, Band VI, Burd EM*, Weiss DS* (2014). Colistin heteroresistance in Enterobacter cloacae is associated with cross-resistance to host antimicrobial lysozyme. Antimicrob Agents Chemother. 58(9):5594-7. *, co- corresponding authors.

Sampson TR, Napier BA, Schroeder MR, Jones CL, Weiss DS. (2014) Enhancement of envelope integrity by a CRISPR/Cas system promotes evasion of the inflammasome. Proc Natl Acad Sci USA. 111(30):11163-8.

Feng Y, Napier BA, Manandhar M, Henke SK, Weiss DS, Cronan JE. (2014). A Francisella virulence factor catalyzes an essential reaction of biotin biosynthesis. Mol Microbiol. 91(2):300-14.

Napier BA, Burd EM, Satola SW, Cagle SM, Ray SM, McGann P, Pohl J, Lesho EP, Weiss DS. (2013). Clinical use of colistin induces cross-resistance to host antimicrobials in Acinetobacter baumannii. mBio. 4(3):e00021-13. *Recommended by Faculty of 1000

Napier BA, Meyer L, Bina JE, Miller MA, Sjöstedt A, Weiss DS. (2012). A link between biotin and rapid phagosomal escape in Francisella. Proc Natl Acad Sci USA. 109(44):1804-89.

Jones CL*, Napier BA*, Sampson TR*, Llewllyn AC, Schroeder MR, Weiss DS. (2012). Subversion of host recognition and defense systems by Francisella spp. Microbiol Mol Biol Rev. 76(2): 383-404. *Authors contributed equally to this manuscript

Llewellyn AC, Zhao J, Song F, Parvathareddy J, Xu Q, Napier BA, Laroui H, Merlin D, Bina JE, Cotter PA, Miller MA, Raetz CR, Weiss DS. (2012). NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis. Mol Microbiol. 86(3):611-27.

Llewellyn AC, Jones CL*, Napier BA*, Bina JE, Weiss DS. (2011). Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence. PloS ONE. 6(9): e24201. *All contributed equally to this manuscript.

Limbago B, Fosheim GE, Schoonover V, Crane CE, Nadle J, Petit S, Heltzel D, Ray SM, Harrison LH, Lynfield R, Dumyati G, Townes JM, Schaffner W, Mu Y, Fridkin SK; Active Bacterial Core surveillance MRSA Investigators. Characterization of methicillin-resistant Staphylococcus aureus isolates collected in 2005 and 2006 from patients with invasive disease: a population-based analysis. J Clin Microbiol. 2009 May;47(5):1344-51.

Satola SW, Napier BA, Farley MM. (2008). Association of IS1016 with the hia adhesion gene and biotypes V and I in invasive nontypeable Haemophilus influenzae. Infect Immun. 76(11):5221-7.